A Head-to-Head Comparison of the Diagnostic Performance of Two Quantitative Tests of Liver Stiffness Estimation in A Cohort of Patients with Compensated Cirrhosis

Background and Aim: We attempted to estimate the Diagnostic Performance of 2D-Shear wave elastography(2D-SWE) Transient elastography (TE) in predicting esophageal varices patients with compensated cirrhosis. It was then compared each other non-invasive modalities estimation liver stiffness. Methods: 108 cirrhosis underwent B-mode ultrasound, 2D-SWE, TE endoscopy. The diagnostic performance these were by AUROCs. Multivariate regression analysis identified risk factors that predicted presence varices. 2D-SWE using Bland-Altman scatter plot, Passing-Bablok Cusum test for linearity. Results: This study comprised 64 males 44 females, mean age 51.73 ± 11.35 years. significant etiologies NASH (40%) alcohol (27%). Sixty-three had varices, while 36 high-risk AUROC (0.967) comparable (0.961), but significantly higher than parameters (platelet count, spleen diameter, platelet count/spleen diameter ratio, FIB-4, APRI). optimal stiffness cut-off value 21.1 kPa 22 respectively. Both a positive correlation On Passing Bablok analysis, there no systematic difference or proportional between two tests. linearity showed deviation from linearity, which means both tests are comparable. Conclusion: assessment This, our knowledge is first directly compare techniques Given various advantages including performing real time Ultrasound scan, it may replace as method choice estimation.